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Detoxification & Digestive Support

Gentle Detox & Digestive Support, Naturally

Sennagex is a natural laxative senna extract for detoxification, gut health and digestive support. High in enriched sennosides, it offers gentle, effective relief, ideal for elderly-friendly and long-term digestive formulations.

About the Ingredient

Sennagex, A Trusted HAD-Free Senna Extract

Sennagex™ is a premium, EU grade senna extract made from carefully selected senna (Cassia angustifolia) leaves. It is developed and manufactured by Ingex Botanicals (P) Limited, India, the manufacturing arm of Ingex Germany GmbH, and supplied to nutraceutical and supplement companies across Europe.

Sennagex™ addresses the critical regulatory bottleneck surrounding Hydroxyanthracene Derivatives (HADs). While traditional senna extracts face increasing scrutiny under stringent EU safety norms, Sennagex™ uses a patented manufacturing process and 100% clean ethanol extraction to remove harmful compounds such as emodin and aloe-emodin while enriching potent sennosides.

Whether you are developing natural laxatives, detox teas, or long-term digestive health supplements, Sennagex™ gives your formulation a high-performance, EU-compliant foundation.

Senna leaves and flowers, the source of Sennagex HAD-Free Senna Extract
NSF · ISO · GMP
Kosher & HALAL Certified
Quick Overview

Sennagex at a Glance

Everything you need to know about this EU grade HAD-free senna ingredient. Origin, the HAD challenge, patented purification, and certifications.

01 / Origin

Origin & Source

Senna (Cassia angustifolia) is one of the most established botanicals for digestive health, traditionally valued for its sennoside content. Sennagex™ brings this trusted heritage into modern nutraceutical science with a clean, standardised, EU-compliant extract.

02 / The Challenge

The HAD Bottleneck

Traditional senna extracts face increasing EU scrutiny over Hydroxyanthracene Derivatives (HADs) such as emodin and aloe-emodin. EU Regulation 2021/468 sets strict thresholds, creating a regulatory bottleneck Sennagex™ is engineered to solve.

03 / The Solution

Patented Purification

Sennagex™ uses a patented manufacturing technology with 100% clean ethanol extraction. This selectively removes harmful HADs while enriching potent sennosides, delivering superior potency and batch-to-batch consistency.

04 / Quality

Certifications

Produced in a facility certified for NSF-GMP, HACCP, and ISO 9001. Sennagex™ is also Kosher and HALAL certified, meeting the quality and regulatory standards required for European supplement and food markets.

Our Strategic Edge

Four Foundations Behind Sennagex

What sets us apart, EU HAD-compliance, clean ethanol extraction, high sennoside enrichment, and patented purification technology.

HADs-Compliant Extract

100% EU Compliant

Meets the strict thresholds of EU Regulation 2021/468

Clean Ethanol Extraction

Harmful solvent-free process

Eco-friendly extraction that protects delicate actives

High Sennoside Enrichment

Superior Potency

Optimised for batch-to-batch consistency in formulations

Patented Technology

Selective HAD Separation

Unique process separating sennosides from harmful HADs
Why Choose Sennagex™

HAD-Free Senna Extract Manufacturers & Suppliers in Europe You Can Trust

From patented HAD purification and full EU compliance to Rotterdam warehouse stock and complete documentation, Sennagex™ is built for European B2B nutraceutical brands.

Why Brands Choose Sennagex™

  • 100% EU compliant HAD-free senna extract
  • Patented purification technology, sennosides separated from HADs
  • 100% clean ethanol extraction, harmful solvent-free
  • NSF-GMP, HACCP, and ISO 9001 certified facility
  • Kosher and HALAL certified, EU market ready
  • EU warehouse in Rotterdam, fast delivery across Europe
  • High sennoside enrichment for superior potency
  • Full batch documentation: CoA, SDS, regulatory support
  • Batch-to-batch consistency for reliable formulations

Health Benefits of Senna

  • Natural laxative: Supports gentle, effective bowel regularity
  • Detoxification: Aids the body’s natural detoxification processes
  • Gut health: Supports healthy digestion and gut motility
  • Digestive support: It would be suited for long-term digestive health supplements
  • Elderly-friendly: Gentle support for age-related reduced gut motility

Versatile Applications

  • Natural laxative capsules, tablets and powders
  • Detox teas and herbal digestive infusions
  • Long-term digestive health supplements
  • Gentle, elderly-friendly bowel regularity formulations

The Breakthrough in HAD-Compliant Detox

Sennagex™ addresses the critical regulatory bottleneck surrounding Hydroxyanthracene Derivatives (HADs). While traditional senna extracts face increasing scrutiny under stringent EU safety norms, Sennagex™ uses a patented manufacturing process and 100% clean ethanol extraction to remove harmful compounds like emodin and aloe-emodin while enriching potent sennosides.

The result is a high-performance, fully compliant senna extract that lets your brand formulate natural laxatives and digestive products with confidence in the European market.

EU Warehouse, Rotterdam, Netherlands

As dedicated senna extract suppliers in Europe, we hold stock at our Rotterdam warehouse for fast, reliable delivery across the EU. No long lead times. Your order ships from the Netherlands.

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Why Sennagex™

Why Sennagex is the Strategic Choice

Sennagex™ HAD-free senna extract is engineered around six core advantages, each designed to give European supplement brands a compliant, high-performance digestive ingredient.

Strategic Advantage Key Property Benefit to Your Formulation
HADs-Compliant Extract 100% EU Compliant Meets EU Regulation 2021/468 thresholds for hydroxyanthracene derivatives
Clean Ethanol Extraction Harmful Solvent-Free Eco-friendly process that maximises purity and protects delicate active compounds
High Sennoside Enrichment Superior Potency Optimised for potency and batch-to-batch consistency in digestive formulations
Elderly-Friendly Solution Gentle & Effective Supports age-related reduced gut motility and irregular bowel movements
Patented Technology Selective Separation Unique manufacturing process that separates active sennosides from harmful HADs
Versatile Applications Multi-Format Ready Ideal for natural laxatives, detox teas and long-term digestive health supplements
Product Specifications

Available Grades & Specifications

Sennagex™ HAD-free senna extract is supplied in a range of standardised grades and forms to meet European supplement, digestive health and detox formulation requirements. Custom specifications available on request.

Grade / Form Standardisation Typical Application
Senna Extract Sennosides 20%, 40% & 60% by HPLC & UV Capsules, tablets, detox teas, long-term digestive health supplements
Senna Extract (Low-Dose) 1.5% Sennosides by HPLC Gentle digestive blends, daily-use wellness formulations
Custom Grade Available on Request Bespoke to customer formulation specifications

Custom specifications can be developed on request. Contact us for certificates of analysis, safety data sheets, and technical documentation.

Evidence-Based

EU Regulatory Compliance

Sennagex™ is engineered around the strict European safety framework for hydroxyanthracene derivatives, redefining digestive safety for senna-based formulations.

Regulatory Framework

EU Regulation 2021/468 and the HAD Safety Framework for Senna Extracts

EU Regulation 2021/468, amending Annex III of Regulation (EC) No 1925/2006 · MinSan Circular, 14/04/2021

EU Regulation 2021/468 introduced monitoring of botanical species containing hydroxyanthracene derivatives (HADs), amending Annex III of Regulation (EC) No 1925/2006. It places traditional senna extracts under increasing regulatory scrutiny.

The MinSan Circular dated 14/04/2021 requires analytical determination of HAD levels, establishing a threshold value of <1 ppm for emodin, <1 ppm for aloe-emodin, and <1 ppm for the sum of Aloin A and Aloin B as a test of the presence of these substances in food preparations with physiological or nutritional functionality.

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How Sennagex Complies

EU HAD threshold framework, EU Regulation 2021/468

Monitored Compound EU Threshold
Emodin <1 ppm
Aloe-Emodin <1 ppm
Sum of Aloin A & Aloin B <1 ppm

PurificationPatented HAD Removal

  • Patented technology separates active sennosides from harmful HADs
  • Removes harmful compounds such as emodin and aloe-emodin
  • 100% clean ethanol extraction, harmful solvent-free process

PerformanceCompliant & High-Performance

  • High sennoside enrichment for superior potency
  • Batch-to-batch consistency for reliable digestive formulations
  • Protects delicate active compounds during extraction
Sennagex™ redefines digestive safety, a 100% EU-compliant, HAD-free senna extract your brand can formulate with confidence.
Need Help?

Frequently Asked Questions

Common questions from nutraceutical and supplement brands in Europe about Sennagex™ HAD-free senna extract.

What is senna extract?
Senna extract is a botanical extract derived from the leaves of the senna plant (Cassia angustifolia). It is one of the most widely used natural laxatives, valued for its sennoside content, which supports healthy bowel movement and digestive regularity. Senna extract is used across Europe and globally in natural laxatives, detox teas, and digestive health supplements.
What are HADs (hydroxyanthracene derivatives) in senna?
Hydroxyanthracene derivatives (HADs) are naturally occurring compounds found in senna and certain other botanicals, including emodin, aloe-emodin, and aloin. Under stringent EU safety norms, these compounds are subject to strict scrutiny and monitoring. Sennagex™ uses a patented purification process to remove these harmful HADs while retaining the beneficial sennosides that deliver senna’s digestive benefits.
Is Sennagex™ compliant with EU Regulation 2021/468?
Yes. Sennagex™ is 100% compliant with EU Regulation 2021/468, which amends Annex III of Regulation (EC) No 1925/2006 regarding botanical species containing hydroxyanthracene derivatives. The regulation, alongside the MinSan Circular dated 14/04/2021, establishes threshold values of 1 ppm for emodin, 1 ppm for aloe-emodin, and 1 ppm for the sum of Aloin A and Aloin B. Sennagex™ is engineered to meet this strict European safety framework.
How does Sennagex™ remove HADs while keeping sennosides?
Sennagex™ uses a patented manufacturing technology combined with 100% clean ethanol extraction. This unique process selectively separates and removes harmful HADs, such as emodin and aloe-emodin, while enriching the potent, beneficial sennosides. The result is a high-performance, EU-compliant senna extract with superior potency and batch-to-batch consistency, all achieved through an eco-friendly, harmful solvent-free process.
What certifications does Sennagex™ hold?
Sennagex™ is manufactured in a facility certified for NSF-GMP (Good Manufacturing Practice), HACCP (Hazard Analysis and Critical Control Points), and ISO 9001. The product is also Kosher and HALAL certified, which makes it suitable for a wide range of consumer markets across Europe. Full documentation, including certificates of analysis and safety data sheets, is available on request.
Is Sennagex™ suitable for elderly digestive support?
Yes. Sennagex™ is specifically designed as an elderly-friendly solution. It provides gentle, effective support for age-related reduced gut motility and irregular bowel movements, making it especially well suited to long-term digestive health supplements aimed at older consumers. Its high sennoside enrichment and HAD-free profile make it a reliable, compliant choice for gentle digestive formulations.
What applications is Sennagex™ suitable for?
Sennagex™ is a versatile ingredient ideal for a range of digestive health applications. It is well suited to natural laxatives in capsule, tablet and powder form, detox teas and herbal digestive infusions, and long-term digestive health supplements. Its gentle, elderly-friendly profile also makes it ideal for formulations targeting age-related bowel regularity. Sennagex™ is designed for B2B nutraceutical, supplement, and functional food brands.
Who manufactures Sennagex™ and how is it produced?
Sennagex™ is manufactured by Ingex Botanicals (P) Limited in India, the manufacturing arm of Ingex Germany GmbH. It is produced from selected senna (Cassia angustifolia) leaves using a patented purification technology and 100% clean ethanol extraction in a GMP, HACCP, and ISO-certified facility. It is then warehoused at our Rotterdam, Netherlands facility and supplied to European nutraceutical and supplement brands through Ingex Germany, with full batch traceability and EU-ready documentation maintained at every stage.
Do you hold senna extract stock in Europe?
Yes. As a dedicated senna extract supplier in Europe, we maintain stock of Sennagex™ at our warehouse in Rotterdam, Netherlands. This allows us to offer fast, reliable delivery to customers across the EU, including Germany, France, Italy, Spain, the Benelux countries, and beyond, without the delays of direct shipping from Asia. Contact us to check current stock availability and lead times.
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Request a sample, bulk quote, or technical documentation for Sennagex™ HAD-free senna extract. Our team responds within one business day.

Or write to us at: enquiry@ingexgermany.de